Longevity interventions encompass a broad range of strategies aimed at slowing, halting, or reversing the aging process. These include lifestyle modifications, pharmaceutical interventions, and emerging biotechnological approaches.
Longevity interventions target the fundamental processes of aging, including cellular senescence, mitochondrial dysfunction, inflammation, and epigenetic changes. The goal is to extend healthspan and potentially lifespan.
- Sleep
- Nutrition
- Exercise
- Relationships
- Purpose
- Stress management: mindfulness, meditation, nature, sunlight, detox
- Habits & routines
- Hormesis:
- Fasting & caloric restriction
- Sauna
- Ice baths
- Supplements
- Nootropics
- Unapproved drugs
- Peptides
- Wearables (SpO2, CGM)
- Consumer OMICs tests
- Plasmapheresis / TPE (Therapeutic Plasma Exchange)
- PRP (Platelet-Rich Plasma)
- IV infusions
- Stem cell therapies
- Red light therapy
- Hyperbaric oxygen therapy
- Body scans
- Metformin for metabolic health
- Rapamycin for mTOR inhibition
- Senolytic drugs for cellular senescence
- NAD+ precursors for cellular energy
- Biomarkers & aging clocks
- Genetic engineering
- Geroprotective drugs
- Senolytics (Dasatinib, Quercetin, BCL-2 inhibitors, p53 pathway modulators)
- Gene therapy: TERT, Klotho, Follistatin
- Cellular reprogramming
- Artificial organs
- Cloning
- Cryopreservation
- Botox, fillers, creams, retinoids
- Liposuction, cosmetic surgery
- Lasers, acne treatments
- Hair restoration, teeth whitening
- Hormone replacement therapy
- Dietary supplements
- Herbal remedies
- Homeopathy
- Acupuncture
- Yoga
- Meditation
- Tai Chi
- Qi Gong
- Reiki
- Ayurveda
- Naturopathy
- Chiropractic
- Aromatherapy
- Bach flower remedies
- Homeopathy
- Ayurveda
- Naturopathy
- Chiropractic
- Aromatherapy
- Bach flower remedies
The evidence quality varies significantly:
- Strong evidence for lifestyle interventions
- Moderate evidence for some pharmaceuticals
- Limited evidence for emerging technologies
- Ongoing research in many areas
Safety profiles vary widely:
- Lifestyle interventions generally safe
- Pharmaceuticals require medical supervision
- Emerging technologies largely experimental
- Individual variation in response